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Sunday 19th March 2017

13:30 - 16:00 Delegate Registration

Session 1: Welcome and Opening Keynote Talks

16:00 - 16:10 Welcome
Professor Timothy Illidge (The University of Manchester, UK)

16:10 - 16:55 Opening Keynote Lecture
Professor Stephen Hahn (MD Anderson Cancer Centre, USA)

"The Future of Radiotherapy"

16:55 - 18:00 The Big Debate: This house believes that biology rather than physics will deliver the biggest advances in radiotherapy over the next 20 years
Chairs: Professor Ranald MacKay (The Christie NHS Foundation Trust, UK) and Professor Catharine West (The University of Manchester, UK)
Professor Susan Short (Leeds Institute of Molecular Medicine, UK)
Professor Tony Lomax (Paul Scherrer Institut, Switzerland)

18:00 - 19:30 Drinks Reception - The Midland Hotel

Monday 20th March 2017

Session 2: Image Guided & Adaptive Radiotherapy

Chairs: Professor Marcel van Herk (The University of Machester, UK) and Dr Ananya Choudhury (The Christie NHS Foundation Trust, UK)

08:50 - 09:15 Professor Hiroki Shirato (Hokkaido University School of Medicine, Japan)

"Real-time-image Gated Proton Beam Therapy"

09 :15 - 09:40 Dr Kristy Brock (University of Michigan, USA)

"Anatomical Modelling to advance the design, delivery, and understanding of radiotherapy"

09:40 - 10:05 Dr Cynthia Eccles (The Royal Marsden NHS Foundation Trust, UK)

"Incorporating MR into routine radiotherapy"

10:05 - 10:30 Dr Jan-Jakob Sonke (Netherlands Cancer Institute, Netherlands)

"CBCT guided and adaptive radiotherapy"

10:30 - 10:55 Coffee break and poster session

Session 3: Realising the Proton Advantage

Chairs: Professor Karen Kirkby (The University of Manchester, UK) and Dr Ed Smith (The Chrsite NHS Foundation Trust, UK)

10:55 - 11:20 Professor Thomas Merchant (St. Jude Children's Research Hospital, USA)

"Insights into treating paediatric cancer with protons"

11:20 - 11:45 Professor Marco Durante (Trento Institute for Fundamental Physics Applications, Italy)

"How laboratory research on protons and carbon ions can inform clinical practice"

11:45 - 12:00 Professor Karen Kirkby (The University of Manchester, UK)

"Proton Therapy- Do we need research?"

12:00 - 12:45 Plenary Lecture
Professor Robert Bristow (Princess Margaret Hospital/ University of Toronto, Canada)

"Precision cancer medicine and radiotherapy in the era of genomic sequencing"

12:45 - 13:45 Lunch and poster session

Session 4: Getting the most from Radiotherapy Drug/Immunomodulatory Combinations

Chairs: Professor Timothy Illidge (The University of Manchester, UK) and Professor Ian Stratford (The University of Manchester, UK)

13:45 - 14:10 Professor Ricky Sharma (University College London, UK)

"New drug-radiotherapy combinations: what is the line of sight?"

14:10 - 14:35 Dr Conchita Vens (Netherlands Cancer Institute, Netherlands)

"DNA damage response inhibitors combined with radiotherapy: where is the therapeutic gain?"

14:35 - 14:50 Professor Timothy Illidge (The University of Manchester, UK)

"Combining radiotherapy and immunotherapy to increase systemic anti-tumour immune responses"

14:50 - 15:15 Professor David Raben (University of Colorado Cancer Centre, USA)

"Radiation therapy and immunotherapy combinations: becoming the firestarter rather than the fire"

15:15 - 15:40 Coffee break and poster session

Session 5: New Visions for Clinical Practice

Chairs: Professor Corinne Faivre-Finn (The University of Manchester, UK) and Professor Nick Slevin (The Christie NHS Foundation Trust, UK)

15:40 - 15:55 Professor Corinne Faivre-Finn (The University of Manchester, UK)

"Manchester-led lung cancer clinical research"

15:55 - 16:20 Professor Dirk de Ruysscher (Maastro Clinic, Netherlands)

"Lung clinical trials: past, present, future"

16:20 - 16:35 Dr David Thomson (The Christie NHS Foundation Trust, UK)

"H&N clinical trials: past, present, future"

16:35 - 17:20 Plenary Lecture
Professor Gillies McKenna (CRUK/MRC Oxford Institute for Radiation Oncology / University of Oxford, UK)

"Do we need physics to solvebiological problems?"

19:00 - Symposium Dinner -Manchester Town Hall

Tuesday 21st March 2017

Session 6: Biological Optimisation

Chairs: Professor Catharine West (The University of Manchester, UK) and Dr Michael Taylor (The Christie NHS Foundation Trust, UK)

08:45 - 09:10 Professor David Azria (Montepellier Cancer Institute, France)

"Data based radiation oncology: design of clinical trials in the toxicity biomarkers era"

09:10 - 09:25 Dr Ananya Choudhury (The Christie NHS Foundation Trust, UK)

"Radiotherapy biomarkers"

09:25 - 09:50 Dr Robert Wilkinson (MedImmune, UK)

"Predicting immune-targeting response"

09:50 - 10:15 Dr Ester Hammond (CRUK/MRC Oxford Institute for Radiation Oncology, UK)

"Exploring the biological response to hypoxia: opportunities to reduce radiation resistance"

10:15 - 10:45 Coffee break and poster session

Session 7: Imaging

Chairs:Dr James O'Connor (The University of Manchester, UK) and Professor Kaye Williams (The University of Manchester, UK)

10:45 - 11:10 Dr Thomas Hambrock (Radboud University Medical Centre, Netherlands)

"PSMA-PET and Ultrasmall iron-oxide nanoparticle MR lymphography for targeted therapy of metastastic prostate cancer"

11:10 - 11:25 Dr James O'Connor (The University of Manchester, UK)

"Translating new MRI biomarkers of hypoxia: example from OE-MRI"

11:25 - 11:40 Professor Kaye Williams (The University of Manchester, UK)

"Evaluating the biological response to radiotherapy using multimodality imaging in preclinical models"

11:40 - 12:00 Lecture- Professor Catharine West (The University of Manchester, UK)

"Hypoxia profiling for precision radiotherapy"

12:00 - 13:00 Lunch and poster session 

Session 8: Quality in Radiotherapy

Chairs: Professor Ranald MacKay (The Christie NHS Foundation Trust, UK) and Dr Julia Handley (The Christie NHS Foundation Trust, UK)

13:00 - 13:25 Professor Peter Hoskin (East and North Hertfordshire NHS Trust, UK)

"The role of clinical trials in improving advanced radiotherapy"

13:25 - 14:50 Dr Catharine Clark (Royal Surrey County Hospital, UK)

"Impact of technical audits in advanced radiotherapy"

13:50 - 14:05 Professor Ranald MacKay (The Christie NHS Foundation Trust, UK)

"Quality assurance for adaptive radiotherapy"

Session 9: Predictive Modelling & Big Data

Chairs: Professor Norman Kirkby (The University of Manchester, UK) and Dr Gillian Whitfield (The Christie NHS Foundation Trust)

14:05 - 14:30 Dr Andre Dekker (Maastro Clinic, Netherlands)

"Big data in radiotherapy, hype or hope?"

14:30 - 14:45 Professor Marcel van Herk (The University of Manchester, UK)

"Learning from every patient- using radiotherapy data to improve radiotherapy treatments"

14:45 - 15:10 Dr Rajesh Jena (Cambridge University Hospitals, UK)

"Novel cloud computing applications in radiation therapy - from patients to pixels"

15:10 - 15:35 Professor Hans Langendijk (University Medical Centre Groningen, Netherlands)

"Should NTCP modelling inform the selection of patients for proton therapy"

15:35 - 16:00 Coffee break

Session 10: Closing Keynote and Remarks

Chair: Professor Catharine West (The University of Manchester, UK)

16:00 - 16:45 Plenary Lecture

Professor Mary Gospodarowicz (University Health Network Toronto, Canada)

"Radiotherapy in the 21st Century: Quo Vadis?"

16:45 - 17:00 Closing remarks