Legacy Projects funded by ACED
Funded through ACED 2019-2025
Our ambition is to deliver a step change in early detection research across areas of unmet or greatest need in the community. We want to make a real impact to the lives of individuals and so focus our research on delivering world-leading basic, translational and clinical research across three key research themes and several disease sites.
The projects listed below were funded through the first five year cycle of the International Alliance for Cancer Early Detection 2019-2025. Some projects listed below will still be active until 2027.
Ex-Vivo Models in Cancer
Developing an Ex Vivo Models in Breast and Lung Cancers
NanoOmics
Title: "NanoOmics: Nanoparticle-enabled multi-omic blood biomarker discovery in early stage Non-Small Cell Lung Cancer", co-led by Dr Marilena Hadjidemetriou.
Limit PCa
Title: "Luminal Index MRI Identification of Treatment critical Prostate Cancer (LIMIT PCa)", with Manchester collaboration
Developing a GM Cancer Plan Biomarker TestBed
Title: "Developing a GM Cancer Plan Biomarker TestBed for Impacting on NHS Pathways: A Breast Cancer Stratification Exemplar", Led by Dr Sacha Howell
The Riskman-TARGET Study
Title: "Tiered integrated diagnostics for the early detection of aggressive Prostate Cancer: The Riskman-TARGET study to develop a novel screening approach for prostate cancer.", co-led by Prof. Ken Muir and Dr Artitaya (Li) Lophatananon.
Risk factors for postpartum breast cancer: developing a model for early detection
Title: "Risk factors for postpartum breast cancer: developing a model for early detection", co-led by Prof. Gareth Evans
Stratifying Risk for Early Detection in Hereditary Breast and Ovarian Cancer
Title: "Stratifying Risk for Early Detection in Hereditary Breast and Ovarian Cancer", co-led by Prof. Gareth Evans
Multiparametric Investigation in Lung Nodules
Title: "Multiparametric Investigation and Stratification of Indeterminate Lung Nodules MISIL1", co-led by Dr Phil Crosbie
REPRESENT: A Community Engagement Roadmap
Title: "REPRESENT: A Community Engagement Roadmap to Improve Participant Representation in Cancer Research Early Detection", co-led by Dr Bella Starling
Interrogating Inflammation and Immunology Markers in EDx: A Lung Cancer Biomarker
Title: "Interrogating Inflammation and Immunology Markers in EDx: A Lung Cancer Biomarker", led by Dr Phil Crosbie
Targeting obesity related microenvironment factors
Title: "Targeting obesity related microenvironment factors for biomarkers avenues of early female reproductive cancer detection.", co-led by Prof. Emma Crosbie
Detection of Early Cancer with Deep Histopathological Analysis
Title: "Detection of Early Cancer with Deep Histopathological Analysis", co-led by Prof. Richard Marais
ELECTRIC
Title: "ELECTRIC: Early Detection of Hereditary Renal Cancer (RCC)", co-led by Dr Emma Woodward
Using HDGC to build a toolkit to distinguish indolent from consequential early cancer lesions
Title: "Using HDGC to build a toolkit to distinguish indolent from consequential early cancer lesions", co-led by Prof. David Wedge